New Advances in the Treatment and Assessment of HPA Axis Dysfunction
Presenter: Thomas Guilliams, PhD
Dates: Feburary 22, 2016 & March 21, 2016
The relationship between stress and chronic dysfunction has been oversimplified, and often wrongly interpreted, as an adrenal issue. Of course, the adrenal glands are part of the response, but they are rarely the "cause" of the dysfunction.
This first lecture will re-orient the clinical perspective of the HPA axis in a detail that is often lacking when stress is discussed in the integrative and functional medicine setting.
Expanding upon our first lecture, we will discuss the various validated methods of assessing HPA axis activity and how the study of stress and clinical outcomes has expanded in the past few decades. We will discuss the different biomarkers (mostly saliva) and therapeutic strategies to modulate stress-related dysfunctions.
- Discuss the implications of using different nomenclature to describe HPA axis dysfunction
- Describe the major categories of stressors which trigger the HPA axis and discuss ways of modulating these stressors
- Outline 7 different ways in which the effects of cortisol can be modulated in a tissue-specific manner
- Discuss the nuances of salivary cortisol and DHEA(S) testing
- Discuss the utility of early morning cortisol analysis (the “CAR”) and the importance of accurate collection times
- Discuss the role of DHEA and other supplements in modulating the HPA axis
- Discuss the role of exercise on cortisol (the good and the bad)